Apache HTTP Configuration

<VirtualHost *:80>
    ServerAdmin webmaster@domain.com
    DocumentRoot /home/kir/domain.com
    ServerName domain.com
    ServerAlias *.domain.com

    #if SSL required
    SSLEngine on 
    SSLCertificateFile /etc/httpd/certs/domain.com/server.crt 
    SSLCertificateKeyFile /etc/httpd/certs/domain.com/server.key
    ErrorLog logs/domain.com-error_log
    CustomLog logs/domain.com-access_log common
    Options -Indexes +FollowSymLinks
    <Directory /home/kir/domain.com>
        RewriteEngine on
        Order allow,deny
        AllowOverride all
        Allow from all
    </Directory>
</VirtualHost>

The parent directory of your DirectoryRoot must be accessible by Apache, so you must make sure that Apache got execute rights for /home/kir
chmod 0755 /home/kir 

or

chown kir:apache /home/kir
chmod 0750 /home/kir

If Running Security Enhanced Linux (SELinux)

Another possibility for this error is that you are running SELinux (Security Enhanced Linux), inwhich case you need to use chcon to apply the proper security context to the directory. One easy way to do this is to copy from a directory that does work for example /var/www/

chcon -R --reference=/var/www /path/to/webroot